H. pylori is a common type of bacteria that grows in the digestive tract and has a tendency to attack the stomach lining. It infects the stomachs of roughly 60 percent trusted Source of the world’s adult population. H. pylori infections are usually harmless, but they’re responsible for the majority of ulcers in the stomach and small intestine.
The “H” in the name is short for Helicobacter. “Helico” means spiral, which indicates that the bacteria are spiral shaped.
Helicobacter pylori often infect your stomach during childhood. While infections with this strain of bacteria typically don’t cause symptoms, they can lead to diseases in some people, including peptic ulcers, and an inflammatory condition inside your stomach known as gastritis.
H. pylori are adapted to live in the harsh, acidic environment of the stomach. These bacteria can change the environment around them and reduce its acidity so they can survive. The spiral shape of helicobacter pylori allows them to penetrate your stomach lining, where they’re protected by mucus and your body’s immune cells are not able to reach them. The bacteria can interfere with your immune response and ensure that they’re not destroyed. This can lead to stomach problems.
Hp fast urease test are used to detect a Helicobacter pylori ( H. pylori) infection in the stomach and upper part of the small intestine (duodenum). H. pylori can cause peptic ulcers. But most people with helicobacter pylori in their digestive systems do not develop ulcers.
It is based on showing the urease enzyme, an enzyme secreted by H.pylori in antral biopsy samples taken during endoscopy. In the presence of urease enzyme, urea in the environment is broken down into ammonia and bicarbonate, raising the pH of the environment, and this change is observed with the pH indicator. 90% of the positive results are found in the first half hour, the rest are read the next day. It is widely used because it is a fast and practical method. Its sensitivity is between 89-98% and specificity between 93-98%.